Reducing False Negative PCR Test for COVID-19
DOI:
https://doi.org/10.21106/ijma.421Keywords:
- SARS-CoV-2,
- COVID-19,
- Real time polymerase chain reaction,
- RT-PCR test,
- Diagnosis,
- False negatives,
- Genetics,
- Emerging disease
Abstract
As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction.
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Copyright © 2020 Fatemeh Bahreini, Rezvan Najafi, Razieh Amini, Salman Khazaei, Saeid Bashirian. Published by Global Health and Education Projects, Inc., USA.
This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , which permits others to remix, transform, and build upon the work non-commercially, provided the original author is credited and the new creations are licensed under the same terms.