Reducing False Negative PCR Test for COVID-19

Authors

  • Fatemeh Bahreini Department of Molecular Medicine and Genetics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
  • Rezvan Najafi Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
  • Razieh Amini Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
  • Salman Khazaei Modeling of Non-communicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
  • Saeid Bashirian Department of Public Health, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran

DOI:

https://doi.org/10.21106/ijma.421

Keywords:

  • SARS-CoV-2,
  • COVID-19,
  • Real time polymerase chain reaction,
  • RT-PCR test,
  • Diagnosis,
  • False negatives,
  • Genetics,
  • Emerging disease

Abstract

As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. Real-time polymerase chain reaction (RT-PCR) is a common molecular test for diagnosing SARS-CoV-2. If some factors are not taken into consideration when performing this test, it can have a relatively large number of false negative results. In this article, we discuss important considerations that could lead to false negative test reduction.

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Published

2020-10-08
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How to Cite

Bahreini, F., Najafi, R., Amini, R., Khazaei, S., & Bashirian, S. (2020). Reducing False Negative PCR Test for COVID-19. International Journal of Maternal and Child Health and AIDS, 9(3), 409–411. https://doi.org/10.21106/ijma.421

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Copyright © 2020 Fatemeh Bahreini, Rezvan Najafi, Razieh Amini, Salman Khazaei, Saeid Bashirian. Published by Global Health and Education Projects, Inc., USA.

Creative Commons License

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License , which permits others to remix, transform, and build upon the work non-commercially, provided the original author is credited and the new creations are licensed under the same terms.